The program, aired on television on Monday, was devoted to the Ukrainian events and Russian President Vladimir Putin's politics.
Three locals independently told the Panorama that they had seen a missile launch vehicle on the territory controlled by the terrorists a few hours before the Boeing incident.
One witness saw the missile system being unloaded from a trailer at about 01:30 p.m. local time in Snizhne town 10 km away from the crash site.
"We watched it being dumped, and when they started Buk's engine, the exhaust smoke filled the town square," he said.
An eyewitness told BBC that the crew members looked like Russian servicemen. "They were well disciplined, unlike the insurgents, and they were not dressed in common camouflage uniform of the Ukrainian army used both by the government troops and the separatists," he said.
"They spoke undefiled Russian, pronouncing "g" in a distinctive way," he said.
His words were confirmed by a second witness adding that the officer who accompanied Buk driving in an SUV spoke with Moscow accent.
If the facts are confirmed, the Kremlin will have to provide explanations to the relatives of 298 passengers and the crew from the downed plane as to why the Russian military operated Buk not far from the place where the brutal murder of the airliner passengers was then committed.
The pro-Russian terrorists deny the existence of the anti-aircraft (AA) missile system Buk in their arsenal. Yet the available videos and photos question the Kremlin's and the pro-Russian separatists' statements that there were no Buk in their possession.
Earlier, Malaysian investigators said that the plane destroyed by the pro-Russian insurgents on July 17 had been shot down by a surface-to-air missile launched from the area controlled by the terrorists.
As previously reported, Malaysian Airlines Boeing-777 shot down on July 17 in the Donetsk region, was flying from Amsterdam to Kuala Lumpur. There were 298 people on board including 192 Dutch, 38 Australians, and 43 Malaysians. All passengers and the crew were killed in the accident.